ARP100

• CAT Number: I002786
• CAS Number: 704888-90-4
• Molecular Formula: C17H20N2O5S
• Molecular Weight: 364.42
• Purity: ≥95%
• Synonyms: ARP100; ARP-100; ARP 100;N-hydroxy-2-[N-(propan-2-yloxy)(4-phenylbenzene)sulfonamido]acetamide
• Target: MMP
• Solubility: Soluble in DMSO
• Storage: 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months).
• IUPAC Name: N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide
• InChI: InChI=1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20)
• InChIKey: PHGLPDURIUEELR-UHFFFAOYSA-N
• SMILES: CC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2

ARP100（Cat No.:I002786）is a selective inhibitor of matrix metalloproteinase-2 (MMP-2), an enzyme involved in the breakdown of extracellular matrix components, playing a key role in tissue remodeling, cancer metastasis, and inflammation. By inhibiting MMP-2, ARP100 effectively reduces tumor invasiveness and angiogenesis, making it a valuable compound in oncology research focused on limiting cancer progression. Its specificity also aids in studying MMP-2’s role in pathological tissue degradation, including cardiovascular and fibrotic conditions. ARP100’s targeted action supports exploration into therapeutic strategies that prevent tissue damage and metastasis in various diseases.

Reference

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