Artemisinin

For research use only. Not for therapeutic Use.

  • CAT Number: A000216
  • CAS Number: 63968-64-9
  • Molecular Formula: C15H22O5
  • Molecular Weight: 282.30
  • Purity: ≥95%
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Artemisinin(Cat No.:A000216)is a natural compound derived from the sweet wormwood plant (Artemisia annua), widely known for its potent antimalarial properties. It contains a unique peroxide bridge that plays a key role in its mechanism of action, disrupting the malaria parasite’s cellular processes. Artemisinin is effective against multidrug-resistant malaria strains and is often used in combination therapies. Its application extends beyond malaria, with research exploring its potential for treating cancer, bacterial infections, and other diseases. Due to its high potency, Artemisinin is essential in global malaria treatment strategies.


Catalog Number A000216
CAS Number 63968-64-9
Synonyms

Arteannuin; 63968-64-9; Artemisinine; Coartem, 63968-64-9; Artemisnini

Molecular Formula C15H22O5
Purity ≥95%
Target PI3K/Akt/mTOR
Storage -20°C
IUPAC Name (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one
InChI InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
InChIKey BLUAFEHZUWYNDE-NNWCWBAJSA-N
SMILES C[C@@H]1CC[C@H]2[C@H](C(=O)O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)C
Reference

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Tangoh DA, Nyingchu RV, Jacob C, Amato R, Djimde A, Kwiatkowski D, Achidi EA,
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Panacea Eligible for Unrestrictive Use? Front Pharmacol. 2017 Oct 17;8:737. doi:
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3: Moore BR, Davis WA, Clarke PM, Robinson LJ, Laman M, Davis TME.
Cost-effectiveness of artemisinin-naphthoquine versus artemether-lumefantrine for
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artemisinin-based combination therapy regimens to treat uncomplicated falciparum
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Imwong M, Miotto O, Patumrat K, Duanguppama J, Cerqueira D, Malleret B, Rénia L,
Nosten S, von Seidlein L, Ling C, Proux S, Corbel V, Simpson JA, Dondorp AM,
White NJ, Nosten FH. Safety and effectiveness of mass drug administration to
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8: Kadioglu O, Chan A, Cong Ling Qiu A, Wong VKW, Colligs V, Wecklein S,
Freund-Henni Rached H, Efferth T, Hsiao WW. Artemisinin Derivatives Target
Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro. Front Pharmacol.
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10: Letchmanan K, Shen SC, Ng WK, Tan RBH. Application of transglycosylated
stevia and hesperidin as drug carriers to enhance biopharmaceutical properties of
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doi: 10.1016/j.colsurfb.2017.10.020. [Epub ahead of print] PubMed PMID: 29054047.

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