For research use only. Not for therapeutic Use.
Artesunate(Cat No.:R008068)is a potent antimalarial drug derived from artemisinin, used primarily for the treatment of severe malaria caused by Plasmodium falciparum. It rapidly kills malaria parasites by generating reactive oxygen species that damage parasitic proteins and membranes. Artesunate is often administered intravenously in critical cases due to its fast-acting nature, making it highly effective in reducing parasitemia and mortality rates. It is typically followed by a full course of oral antimalarials. Artesunate’s efficacy and safety profile make it a vital treatment option in malaria-endemic regions.
Catalog Number | R008068 |
CAS Number | 88495-63-0 |
Synonyms | Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester; Artesunic Acid; |
Molecular Formula | C19H28O8 |
Purity | 98% |
Target | EXP-1 |
Target Protein | P04926 |
Appearance | Solid |
Storage | Dry, dark and at 2 - 8 °C for six months or -20°C for two years. |
IUPAC Name | 4-oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid |
InChI | InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16-,17-,18-,19-/m1/s1 |
InChIKey | FIHJKUPKCHIPAT-AHIGJZGOSA-N |
SMILES | C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC(=O)CCC(=O)O)C |