Asapiprant（Cat No.:R034200）is a selective prostaglandin D2 receptor 1 (DP1) antagonist, developed for its potential to treat allergic and inflammatory conditions, including asthma and allergic rhinitis. By blocking the DP1 receptor, Asapiprant inhibits the action of prostaglandin D2, a key mediator in allergic reactions and inflammation, helping to reduce symptoms like bronchoconstriction and nasal congestion. It has also been explored for its potential in treating cardiovascular and respiratory diseases due to its ability to modulate inflammatory pathways, offering a novel approach to managing these conditions.
| Catalog Number | R034200 |
| CAS Number | 932372-01-5 |
| Synonyms | 2-[5-[4-[[4-(1-Methylethoxy)phenyl]sulfonyl]-1-piperazinyl]-2-(2-oxazolyl)phenoxy]-acetic Acid |
| Molecular Formula | C₂₄H₂₇N₃O₇S |
| Purity | ≥95% |
| Target | DP1 receptor antagonist |
| Storage | -20°C |
| IUPAC Name | 2-[2-(1,3-oxazol-2-yl)-5-[4-(4-propan-2-yloxyphenyl)sulfonylpiperazin-1-yl]phenoxy]acetic acid |
| InChI | InChI=1S/C24H27N3O7S/c1-17(2)34-19-4-6-20(7-5-19)35(30,31)27-12-10-26(11-13-27)18-3-8-21(24-25-9-14-32-24)22(15-18)33-16-23(28)29/h3-9,14-15,17H,10-13,16H2,1-2H3,(H,28,29) |
| InChIKey | ZMZNWNTZRWXTJU-UHFFFAOYSA-N |
| SMILES | CC(C)OC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C3=CC(=C(C=C3)C4=NC=CO4)OCC(=O)O |
