For research use only. Not for therapeutic Use.
Ascorbyl palmitate（Cat No.:I001456） is a compound formed by esterifying ascorbic acid (vitamin C) with palmitic acid, resulting in a fat-soluble form of vitamin C. This esterification process allows for improved stability and solubility in lipid-based systems. Ascorbyl palmitate is commonly used as an antioxidant food additive, especially in fatty and oil-based food products, to prevent oxidation and extend shelf life. It functions by scavenging free radicals and inhibiting the oxidation of lipids, thus preserving the quality and freshness of food products.
| Catalog Number | I001456 |
| CAS Number | 137-66-6 |
| Molecular Formula | C22H38O7 |
| Purity | ≥95% |
| Target | Reactive Oxygen Species; Endogenous Metabolite |
| Solubility | DMSO: ≥ 30 mg/mL |
| Storage | 2-8°C |
| IUPAC Name | [(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] hexadecanoate |
| InChI | InChI=1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1 |
| InChIKey | QAQJMLQRFWZOBN-LAUBAEHRSA-N |
| SMILES | CCCCCCCCCCCCCCCC(=O)OCC(C1C(=C(C(=O)O1)O)O)O |
| Reference | </br>1:Encapsulation and antioxidant activity of ascorbyl palmitate with maize starch during pasting. Bamidele OP, Duodu KG, Emmambux MN.Carbohydr Polym. 2017 Jun 15;166:202-208. doi: 10.1016/j.carbpol.2017.02.095. Epub 2017 Feb 27. PMID: 28385224 </br>2:Encapsulation of the antioxidant ascorbyl palmitate in V-type granular cold-water swelling starch affects the properties of both. Dries DM, Knaepen L, Goderis B, Delcour JA.Carbohydr Polym. 2017 Jun 1;165:402-409. doi: 10.1016/j.carbpol.2017.02.057. Epub 2017 Feb 20. PMID: 28363566 </br>3:Development of an infusion method for encapsulating ascorbyl palmitate in V-type granular cold-water swelling starch. Dries DM, Gomand SV, Pycarelle SC, Smet M, Goderis B, Delcour JA.Carbohydr Polym. 2017 Jun 1;165:229-237. doi: 10.1016/j.carbpol.2017.02.054. Epub 2017 Feb 17. PMID: 28363545 </br>4:Towards Celiac-safe foods: Decreasing the affinity of transglutaminase 2 for gliadin by addition of ascorbyl palmitate and ZnCl<sub>2</sub> as detoxifiers. Engstrom N, Saenz-Méndez P, Scheers J, Scheers N.Sci Rep. 2017 Dec;7(1):77. doi: 10.1038/s41598-017-00174-z. Epub 2017 Mar 6. PMID: 28250436 Free PMC Article</br>5:Ascorbyl palmitate/d-α-tocopheryl polyethylene glycol 1000 succinate monoester mixed micelles for prolonged circulation and targeted delivery of compound K for antilung cancer therapy in vitro and in vivo. Zhang Y, Tong D, Che D, Pei B, Xia X, Yuan G, Jin X.Int J Nanomedicine. 2017 Jan 16;12:605-614. doi: 10.2147/IJN.S119226. eCollection 2017. PMID: 28144142 Free PMC Article</br>6:Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers. Khan H, Akhtar N, Ali A.Drug Res (Stuttg). 2017 Jan;67(1):52-58. doi: 10.1055/s-0042-118171. Epub 2016 Oct 18. PMID: 27756097 </br>7:Chemometric approach to develop frying stable sunflower oil blends stabilized with oleoresin rosemary and ascorbyl palmitate. Upadhyay R, Sehwag S, Niwas Mishra H.Food Chem. 2017 Mar 1;218:496-504. doi: 10.1016/j.foodchem.2016.09.105. Epub 2016 Sep 17. PMID: 27719941 </br>8:Multivariate optimization of a synergistic blend of oleoresin sage (Salvia officinalis L.) and ascorbyl palmitate to stabilize sunflower oil. Upadhyay R, Mishra HN.J Food Sci Technol. 2016 Apr;53(4):1919-28. doi: 10.1007/s13197-015-2157-9. Epub 2015 Dec 30. PMID: 27413218 Free PMC Article</br>9:Inhibition of collagen synthesis by select calcium and sodium channel blockers can be mitigated by ascorbic acid and ascorbyl palmitate. Ivanov V, Ivanova S, Kalinovsky T, Niedzwiecki A, Rath M.Am J Cardiovasc Dis. 2016 May 18;6(2):26-35. eCollection 2016. PMID: 27335688 Free PMC Article</br>10:Electrochemical assay of the antioxidant ascorbyl palmitate in mixed medium. Teneva O, Dimcheva N.Food Chem. 2016 Jul 15;203:35-40. doi: 10.1016/j.foodchem.2016.02.008. Epub 2016 Feb 2. PMID: 26948586 |
