Asenapine maleate

• CAT Number: I000516
• CAS Number: 85650-56-2
• Molecular Formula: C17H16ClNO.C4H4O4
• Molecular Weight: 401.84
• Purity: ≥95%
• Synonyms: Org 5222; Org5222; Org-5222; HSDB 8061; HSDB-8061; HSDB8061; Asenapine; Asenapine maleate; trade names Saphris and Sycrest.;(3aS,12bS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole maleate
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO, not in water
• Storage: 3 years -20C powder
• Related CAS: 65576-45-6(free base)
• IUPAC Name: (Z)-but-2-enedioic acid;(2S,6S)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene
• InChI: InChI=1S/C17H16ClNO.C4H4O4/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19;5-3(6)1-2-4(7)8/h2-8,14-15H,9-10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,15-;/m1./s1
• InChIKey: GMDCDXMAFMEDAG-CHHFXETESA-N
• SMILES: CN1C[C@H]2[C@H](C1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24.C(=C\C(=O)O)\C(=O)O

Asenapine maleate（Cat No.:I000516）is an atypical antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. It works by affecting neurotransmitters in the brain, particularly dopamine and serotonin, helping to balance their activity. This can reduce symptoms such as delusions, hallucinations, mood swings, and aggression. Asenapine is administered either sublingually or as an injection, and it has the advantage of being less likely to cause certain side effects, such as weight gain, compared to other antipsychotics. Common side effects include dizziness, drowsiness, and a dry mouth. It is prescribed when other treatments are ineffective.

Overview of Clinical Research

Asenapine maleate is an alpha adrenergic receptor antagonist and a dopamine receptor antagonist developed by AbbVie.