Asfotase alfa

• CAT Number: I042680
• CAS Number: 1174277-80-5
• Purity: ≥95%

Asfotase alfa（Cat No.:I042680）is a recombinant enzyme therapy used to treat hypophosphatasia, a rare genetic disorder characterized by defective bone mineralization due to low levels of tissue-nonspecific alkaline phosphatase (TNSALP). Asfotase alfa works by replacing the deficient enzyme, thereby improving bone mineralization and reducing skeletal abnormalities. This therapy has shown efficacy in both pediatric and adult patients, particularly in improving mobility, bone strength, and quality of life. Approved by regulatory agencies, asfotase alfa represents a significant advancement in treating hypophosphatasia, a condition with previously limited treatment options.