Asperphenamate

• CAT Number: R074549
• CAS Number: 63631-36-7
• PubChem Substance ID: 173952
• Molecular Formula: C32H30N2O4
• Molecular Weight: 506.60
• Purity: 95%
• Target: Metabolic Enzyme/Protease
• Appearance: White to off-white solid
• Analysis method: HPLC
• IUPAC Name: [(2S)-2-benzamido-3-phenylpropyl] (2S)-2-benzamido-3-phenylpropanoate
• InChI: InChI=1S/C32H30N2O4/c35-30(26-17-9-3-10-18-26)33-28(21-24-13-5-1-6-14-24)23-38-32(37)29(22-25-15-7-2-8-16-25)34-31(36)27-19-11-4-12-20-27/h1-20,28-29H,21-23H2,(H,33,35)(H,34,36)/t28-,29-/m0/s1
• InChIKey: CVULDJMCSSACEO-VMPREFPWSA-N
• SMILES: C1=CC=C(C=C1)CC(COC(=O)C(CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3)NC(=O)C4=CC=CC=C4

Asperphenamate (Cat No.: R074549)is an unusual ester of N-benzoylphenylalanine and N-benzoylphenylalaninol isolated from Aspergillus flavipes and first reported by Clark and co-workers in 1977. Since then, asperphenamate has been found in a broad range of Pencillium and Aspergillus species and even in plants, as a product of endophytic fungi. Asperphenamate has weak antitumor activity. Recently, a more soluble analogue, BBP, was found to induce autophagic cell death in tumor cells, a process modulated by a JNK-dependent Atg4 upregulation involving ROS production.