Astragalin

• CAT Number: I003685
• CAS Number: 480-10-4
• Molecular Formula: C21H20O11
• Molecular Weight: 448.38
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: 3 years -20C powder

Astragalin (CAT: I003685), also known as kaempferol 3-glucoside, is a flavonoid compound found in various plants, including Astragalus and Morus species. It possesses antioxidant, anti-inflammatory, and anti-cancer properties. Astragalin has been shown to scavenge free radicals, reduce oxidative stress, and inhibit inflammatory mediators, contributing to its potential in preventing chronic diseases. Additionally, it exhibits anticancer effects by inhibiting cell proliferation, inducing apoptosis, and suppressing tumor growth. Astragalin also has potential applications in cardiovascular health, neuroprotection, and diabetes management.

Reference

[1]. Cho IH, et al. Astragalin inhibits airway eotaxin-1 induction and epithelial apoptosis through modulating oxidative stress-responsive MAPK signaling. BMC Pulm Med. 2014 Jul 29;14:122.

[2]. Li F, et al. Inhibitory effects of astragalin on lipopolysaccharide-induced inflammatory response in mouse mammary epithelial cells. J Surg Res. 2014 Dec;192(2):573-81.

[3]. Li F, et al. Astragalin suppresses inflammatory responses via down-regulation of NF-κB signaling pathway in lipopolysaccharide-induced mastitis in a murine model. Int Immunopharmacol. 2013 Oct;17(2):478-82.

[4]. Kim MS, et al. Inhibitory effect of astragalin on expression of lipopolysaccharide-induced inflammatory mediators through NF-κB in macrophages. Arch Pharm Res. 2011 Dec;34(12):2101-7.

[5]. Soromou LW, et al. Astragalin attenuates lipopolysaccharide-induced inflammatory responses by down-regulating NF-κB signaling pathway. Biochem Biophys Res Commun. 2012 Mar 9;419(2):256-61.