Atazanavir

• CAT Number: A000018
• CAS Number: 198904-31-3
• Molecular Formula: C₃₈H₅₂N₆O₇
• Molecular Weight: 704.86
• Purity: ≥95%
• Synonyms: Latazanavir, Zrivada, Reyataz, BMS-232632
• Target: HIV Protease
• Solubility: >28.6mg/mL in DMSO
• Storage: Store at -20°C
• InChI: InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,3
• InChIKey: AXRYRYVKAWYZBR-GASGPIRDSA-N
• SMILES: CC(C)(C)C(C(=O)NC(CC1=CC=CC=C1)C(CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)C(C(C)(C)C)NC(=O)OC)O)NC(=O)OC

Atazanavir is an antiretroviral drug of the protease inhibitor (PI) class. It is sold under the trade name Reyataz. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus. Atazanavir is distinguished from other PIs in that it can be given once-daily and has lesser effects on the patient/’s lipid profile. Like other protease inhibitors, it is used only in combination with other HIV medications.

Reference

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