ATB-346

For research use only. Not for therapeutic Use.

  • CAT Number: I000874
  • CAS Number: 1226895-20-0
  • Molecular Formula: C21H19NO3S
  • Molecular Weight: 365.45
  • Purity: ≥95%
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ATB 346(Cat No.:I000874) is a novel derivative of naproxen, a nonsteroidal anti-inflammatory drug (NSAID). What sets ATB 346 apart is its ability to release hydrogen sulfide, which confers additional pharmacological benefits. ATB 346 retains the COX (cyclooxygenase) inhibitory activity of naproxen, providing anti-inflammatory effects. Moreover, it exhibits reduced toxicity compared to traditional NSAIDs. In addition to its anti-inflammatory properties, ATB 346 has shown the ability to induce apoptosis (programmed cell death) specifically in human melanoma cells, suggesting its potential as an anti-cancer agent.


CAS Number 1226895-20-0
Synonyms

4-carbamothioylphenyl 2-(6-methoxynaphthalen-2-yl)propanoate

Molecular Formula C21H19NO3S
Purity ≥95%
Target Apoptosis
Solubility DMSO: ≥ 51.6 mg/mL
Storage Store at -20°C
IUPAC Name (4-carbamothioylphenyl) 2-(6-methoxynaphthalen-2-yl)propanoate
InChI InChI=1S/C21H19NO3S/c1-13(21(23)25-18-8-5-14(6-9-18)20(22)26)15-3-4-17-12-19(24-2)10-7-16(17)11-15/h3-13H,1-2H3,(H2,22,26)
InChIKey YCNMAPLPQYQJFC-UHFFFAOYSA-N
SMILES CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OC3=CC=C(C=C3)C(=S)N

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