For research use only. Not for therapeutic Use.
ATF3 inducer 1 is a potent ATF3 inducer. ATF3 inducer 1 increases the ATF3 protein and ATF3 mRNA expression. ATF3 inducer 1 shows anti-MetS activity in mouse[1].
ATF3 inducer 1 (compound 16c) (50 μM; 8 days) increases the ATF3 protein and ATF3 mRNA expression in 3T3-L1 cells[1].
ATF3 inducer 1 (40 mg/kg; i.p.; three times a week for 10-weeks) shows anti-MetS (managing metabolic syndrome) activity in mouse[1].
| Catalog Number | I042385 |
| Synonyms | 7-methoxy-3-methyl-2H-chromeno[4,3-c]pyrazol-4-one |
| Molecular Formula | C12H10N2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C12H10N2O3/c1-6-10-11(14-13-6)8-4-3-7(16-2)5-9(8)17-12(10)15/h3-5H,1-2H3,(H,13,14) |
| InChIKey | XAKSOGPEDDVQGM-UHFFFAOYSA-N |
| SMILES | CC1=C2C(=NN1)C3=C(C=C(C=C3)OC)OC2=O |
| Reference | [1]. Chang YH, et al. Exploration and biological evaluation of 7-methoxy-3-methyl-1H-chromeno[4,3-c]pyrazol-4-one as an activating transcription factor 3 inducer for managing metabolic syndrome. Eur J Med Chem. 2022 Nov 25;246:114951. |
