For research use only. Not for therapeutic Use.
ATG12-ATG3 inhibitor 1 (compound 189) is a potent inhibitor of autophage[1].
Catalog Number | I040168 |
CAS Number | 333351-38-5 |
Synonyms | N-(4-hydroxynaphthalen-1-yl)-2,4-dimethylbenzenesulfonamide |
Molecular Formula | C18H17NO3S |
Purity | ≥95% |
InChI | InChI=1S/C18H17NO3S/c1-12-7-10-18(13(2)11-12)23(21,22)19-16-8-9-17(20)15-6-4-3-5-14(15)16/h3-11,19-20H,1-2H3 |
InChIKey | BUAHBIAKRIDOHI-UHFFFAOYSA-N |
SMILES | CC1=CC(=C(C=C1)S(=O)(=O)NC2=CC=C(C3=CC=CC=C32)O)C |
Reference | [1]. Gal Chaim Nuta, et al. Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction. Autophagy. 2023 Aug;19(8):2372-2385. |