ATN-161

• CAT Number: I002899
• CAS Number: 262438-43-7
• Molecular Formula: C23H35N9O8S
• Molecular Weight: 597.64
• Purity: ≥95%
• Target: Integrin
• Solubility: 10 mM in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: (2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-acetylpyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-sulfanylpropanoyl]amino]butanediamide
• InChI: InChI=1S/C23H35N9O8S/c1-11(34)32-4-2-3-17(32)23(40)29-14(5-12-7-26-10-27-12)20(37)30-15(8-33)21(38)31-16(9-41)22(39)28-13(19(25)36)6-18(24)35/h7,10,13-17,33,41H,2-6,8-9H2,1H3,(H2,24,35)(H2,25,36)(H,26,27)(H,28,39)(H,29,40)(H,30,37)(H,31,38)/t13-,14-,15-,1
• InChIKey: MMHDBUJXLOFTLC-WOYTXXSLSA-N
• SMILES: O=C(N)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]1N(C(C)=O)CCC1)=O)CC2=CN=CN2)=O)CO)=O)CS)=O)CC(N)=O

ATN-161 (CAT: I002899) is a five-amino-acid peptide derived from the synergy region of fibronectin, functioning as a β integrin antagonist. By targeting integrins, particularly those involved in cell adhesion, migration, and angiogenesis, ATN-161 disrupts tumor cell interactions with the extracellular matrix, thereby inhibiting tumor growth and metastasis. This peptide has demonstrated significant antitumor activity and is particularly valuable in oncology research for exploring integrin-mediated signaling pathways and developing novel cancer therapeutics. Its specificity and effectiveness make it a promising candidate for integrin-targeted cancer treatment strategies.