Atorvastatin-Amlodipine Adduct

For research use only. Not for therapeutic Use.

  • CAT Number: C000053
  • CAS Number: 425408-16-8
  • Molecular Formula: C₅₃H₅₈ClFN₄O₉
  • Molecular Weight: 949.5
  • Purity: ≥95%
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Atorvastatin-Amlodipine Adduct (CAT: C000053) is an innovative amlodipine/atorvastatin amide prodrug, designed to combine the therapeutic benefits of amlodipine, a calcium channel blocker for hypertension and angina, with atorvastatin, a statin medication for lowering cholesterol. This prodrug offers a convenient treatment option for patients with both conditions, enhancing medication adherence and therapeutic effectiveness by releasing the active ingredients in a controlled manner.


Catalog Number C000053
CAS Number 425408-16-8
Synonyms

3-Ethyl 5-Methyl 4-(2-Chlorophenyl)-2-[[2-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate

Molecular Formula C₅₃H₅₈ClFN₄O₉
Purity ≥95%
Solubility DMSO (Slightly, Sonicated), Methanol (Slightly)
Appearance White to Off-White Solid
Storage -20°C, Inert atmosphere
Reference

Crook, Robert J., et al.: Eur. Pat. Appl., EP 1205477 A1 20020515 (2002)

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