For research use only. Not for therapeutic Use.
Atorvastatin Calcium(Cat No.:A001047)is a widely prescribed statin medication used to lower cholesterol levels and reduce the risk of cardiovascular disease. By inhibiting HMG-CoA reductase, an enzyme critical in cholesterol biosynthesis, atorvastatin decreases LDL cholesterol and triglycerides while modestly increasing HDL cholesterol. This helps prevent atherosclerosis, heart attacks, and strokes. Atorvastatin’s high efficacy and favorable safety profile make it suitable for patients with hyperlipidemia or those at high cardiovascular risk. It is also studied for its potential anti-inflammatory and plaque-stabilizing effects, supporting its broader role in cardiovascular health management.
Catalog Number | A001047 |
CAS Number | 134523-03-8 |
Synonyms | NA |
Molecular Formula | C33H35FN2O5 • 1/2Ca |
Purity | ≥95% |
Target | HMG-CoA Reductase |
Solubility | >57.8mg/mL in DMSO |
Storage | 3 years -20C powder |
IUPAC Name | (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid |
InChI | InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1 |
InChIKey | XUKUURHRXDUEBC-KAYWLYCHSA-N |
SMILES | CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4 |