ATPO

• CAT Number: I022627
• CAS Number: 252930-37-3
• Molecular Formula: C11H19N2O7P
• Molecular Weight: 322.25
• Purity: 98%
• Synonyms: ATPO
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
• IUPAC Name: 2-Amino-3-[5-tert-butyl-3-(phosphonomethoxy)-1,2-oxazol-4-yl]propanoic acid
• InChI: InChI=1S/C11H19N2O7P/c1-11(2,3)8-6(4-7(12)10(14)15)9(13-20-8)19-5-21(16,17)18/h7H,4-5,12H2,1-3H3,(H,14,15)(H2,16,17,18)
• InChIKey: AGSOOCUNMTYPSE-UHFFFAOYSA-N
• SMILES: O=C(O)C(N)CC1=C(C(C)(C)C)ON=C1OCP(O)(O)=O

ATPO (Cat.No:I022627) is a potent and Selective Ampa Receptor Antagonist. Inquire ATPO online by filling out the inquiry form, we will get back to you within 24 hours!

Reference

1: Hong A, Stokes B, Otahal P, Owens D, Burgess JR. Temporal trends for thyroid stimulating hormone (TSH) and thyroid peroxidase antibody (ATPO) testing across two phases of iodine fortification in tasmania (1995-2013). Clin Endocrinol (Oxf). 2017 May 13. doi: 10.1111/cen.13371. [Epub ahead of print] PubMed PMID: 28500624.
2: Dauksiene D, Petkeviciene J, Klumbiene J, Verkauskiene R, Vainikonyte-Kristapone J, Seibokaite A, Ceponis J, Sidlauskas V, Daugintyte-Petrusiene L, Norkus A, Zilaitiene B. Factors Associated with the Prevalence of Thyroid Nodules and Goiter in Middle-Aged Euthyroid Subjects. Int J Endocrinol. 2017;2017:8401518. doi: 10.1155/2017/8401518. Epub 2017 Mar 5. PubMed PMID: 28356911; PubMed Central PMCID: PMC5357546.
3: Mikos H, Mikos M, Niedziela M. Diagnostic significance of serum concentrations of soluble Fas ligand (sFasL) in children with autoimmune thyroid disease. Autoimmunity. 2017 May;50(3):192-198. doi: 10.1080/08916934.2017.1289180. Epub 2017 Feb 21. PubMed PMID: 28276714.
4: Wielosz E, Majdan M, Koszarny A, Dryglewska M, Tabarkiewicz J. Systemic sclerosis and organ – specific antibodies. Pol Arch Med Wewn. 2016 Oct 5. doi: 10.20452/pamw.3583. [Epub ahead of print] PubMed PMID: 27848930.
5: Møllerud S, Frydenvang K, Pickering DS, Kastrup JS. Lessons from crystal structures of kainate receptors. Neuropharmacology. 2017 Jan;112(Pt A):16-28. doi: 10.1016/j.neuropharm.2016.05.014. Epub 2016 May 26. Review. PubMed PMID: 27236079.
6: Anila KR, Nayak N, Jayasree K. Cytomorphologic spectrum of lymphocytic thyroiditis and correlation between cytological grading and biochemical parameters. J Cytol. 2016 Jul-Sep;33(3):145-149. PubMed PMID: 27756987; PubMed Central PMCID: PMC4995872.
7: Côté CL, Yip AM, MacLeod JB, O’Reilly B, Murray J, Ouzounian M, Brown CD, Forgie R, Pelletier MP, Hassan A. Efficacy of intraoperative cell salvage in decreasing perioperative blood transfusion rates in first-time cardiac surgery patients: a retrospective study. Can J Surg. 2016 Sep;59(5):330-6. PubMed PMID: 27668331; PubMed Central PMCID: PMC5042720.
8: Szepietowska B, Wawrusiewicz-Kurylonek N, Krętowski A, Górska M, Szelachowska M. Endocrine autoimmunity in patients with Latent Autoimmune Diabetes in Adults (LADA) — association with HLA genotype. Endokrynol Pol. 2016;67(2):197-201. doi: 10.5603/EP.a2016.0017. PubMed PMID: 26884287.
9: Piciu A, Andrianou XD, Irimie A, Bălăcescu O, Zira C, BĂRBUş E, Peştean C, Aristeidou K, Theofanous T, Agathokleous M, Piciu D, Makris KC. Investigation of thyroid nodules in the female population in Cyprus and in Romania. Clujul Med. 2015;88(4):494-9. doi: 10.15386/cjmed-518. Epub 2015 Nov 15. PubMed PMID: 26733748; PubMed Central PMCID: PMC4689243.
10: Jonak O, Połubok J, Barg E. Graves’ disease in 2.5 years old girl – 6-years-long observation. Pediatr Endocrinol Diabetes Metab. 2016;22(2):76-79. doi: 10.18544/PEDM-22.02.0055. PubMed PMID: 28329777.
11: Giejda K, Piszczek S, Stembrowicz-Nowakowska Z, Saracyn M, Dziuk M, Kamiński G. Incidentally recognised thyroid focal uptake of 99mTc-sestamibi during stress myocardial perfusion scintigraphy. Endokrynol Pol. 2015;66(6):521-5. doi: 10.5603/EP.2015.0064. PubMed PMID: 26662651.
12: Drobniak A, Kanecki K, Grymowicz M, Radowicki S. Serum leptin concentration in women of reproductive age with euthyroid autoimmune thyroiditis. Gynecol Endocrinol. 2016;32(2):128-31. doi: 10.3109/09513590.2015.1092512. Epub 2015 Oct 6. PubMed PMID: 26440361.
13: Kamronn S, Poulsen AT, Hansen LK. Multiview Bayesian Correlated Component Analysis. Neural Comput. 2015 Oct;27(10):2207-30. doi: 10.1162/NECO_a_00774. Epub 2015 Aug 27. PubMed PMID: 26313603.
14: Manavela M, Vigovich C, Danilowicz K, Juri A, Miechi L, Fernandez Valoni V, Bruno OD. Thyroid autoimmune disorders in patients with acromegaly. Pituitary. 2015 Dec;18(6):912-5. doi: 10.1007/s11102-015-0670-5. PubMed PMID: 26163018.
15: Chaykivska Z, Antoszczyk G, Czarnobilska E. [The elevated level of anti-thyroid antibodies aTPO in chronic spontaneous urticaria]. Przegl Lek. 2015;72(12):736-8. Polish. PubMed PMID: 27024950.
16: Koukkou E, Kravaritis S, Mamali I, Markantes GG, Michalaki M, Adonakis GG, Georgopoulos NA, Markou KB. No increase in renal iodine excretion during pregnancy: a telling comparison between pregnant women and their spouses. Hormones (Athens). 2014 Jul-Sep;13(3):375-81. doi: 10.14310/horm.2002.1487. PubMed PMID: 25079462.
17: Jørgensen L, Nielsen B, Pickering DS, Kristensen AS, Frydenvang K, Madsen U, Clausen RP. Analogues of 3-hydroxyisoxazole-containing glutamate receptor ligands based on the 3-hydroxypyrazole-moiety: design, synthesis and pharmacological characterization. Neurochem Res. 2014 Oct;39(10):1895-905. doi: 10.1007/s11064-014-1332-0. Epub 2014 May 22. PubMed PMID: 24848194.
18: Rogowicz-Frontczak A, Zozuliłska-Ziołkiewicz D, Litwinowicz M, Niedźwiecki P, Wyka K, Wierusz-Wysocka B. Are zinc transporter type 8 antibodies a marker of autoimmune thyroiditis in non-obese adults with new-onset diabetes? Eur J Endocrinol. 2014 Mar 14;170(4):651-8. doi: 10.1530/EJE-13-0901. Print 2014 Apr. PubMed PMID: 24480135.
19: Koszarny A, Majdan M, Suszek D, Wielosz E, Dryglewska M. Relationship between rheumatoid arthritis activity and antithyroid antibodies. Pol Arch Med Wewn. 2013;123(7-8):394-400. Epub 2013 Jun 21. PubMed PMID: 23792346.
20: Marconcini ML, Fayad L, Shiozawa MB, Dantas-Correa EB, Lucca Schiavon Ld, Narciso-Schiavon JL. Autoantibody profile in individuals with chronic hepatitis C. Rev Soc Bras Med Trop. 2013 Mar-Apr;46(2):147-53. doi: 10.1590/0037-8682-0039-2013. PubMed PMID: 23740063.