Atractylenolide III

• CAT Number: I004719
• CAS Number: 73030-71-4
• Molecular Formula: C15H20O3
• Molecular Weight: 248.32
• Purity: ≥95%
• Target: Apoptosis
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C

Atractylenolide III (CAT: I004719) is a natural compound derived from the medicinal herb Atractylodes macrocephala. It belongs to the class of sesquiterpene lactones and exhibits various pharmacological activities. Atractylenolide III has been found to possess anti-inflammatory, immunomodulatory, and anti-tumor properties. It inhibits the production of inflammatory mediators, such as nitric oxide and pro-inflammatory cytokines, and modulates immune cell function. Additionally, it has shown potential in inhibiting the growth and proliferation of cancer cells. Atractylenolide III has been studied for its therapeutic potential in various inflammatory disorders and cancers, highlighting its importance as a natural product with promising pharmacological properties.

Reference

[1]. Kang TH, et al. Atractylenolide III, a sesquiterpenoid, induces apoptosis in human lung carcinoma A549 cells via mitochondria-mediated death pathway. Food Chem Toxicol. 2011 Feb;49(2):514-9.

[2]. Wang KT, et al. Gastroprotective activity of atractylenolide III from Atractylodes ovata on ethanol-induced gastric ulcer in vitro and in vivo. J Pharm Pharmacol. 2010 Mar;62(3):381-8.

[3]. Kim HK, et al. Toxicity of atractylon and atractylenolide III Identified in Atractylodes ovata rhizome to Dermatophagoides farinae and Dermatophagoides pteronyssinus. J Agric Food Chem. 2007 Jul 25;55(15):6027-31.