Atracurium Besylate

• CAT Number: A000487
• CAS Number: 64228-81-5
• Molecular Formula: C65H82N2O18S2
• Molecular Weight: 1243.50
• Purity: ≥95%
• Synonyms: Atracurium besilate; 64228-81-5; Tracrium; Atracurii besilas; Besilate d/’atracurium
• Target: Neuronal Signaling
• Storage: -20°C
• IUPAC Name: benzenesulfonate;5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate
• InChI: InChI=1S/C53H72N2O12.2C6H6O3S/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6;2*7-10(8,9)6-4-2-1-3-5-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3;2*1-5H,(H,7,8,9)/q+2;;/p-2
• InChIKey: XXZSQOVSEBAPGS-UHFFFAOYSA-L
• SMILES: C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-]

Atracurium Besylate（Cat No.:A000487）is a non-depolarizing neuromuscular blocker used during surgical procedures and mechanical ventilation to induce muscle relaxation. It works by competitively binding to nicotinic acetylcholine receptors at the neuromuscular junction, preventing acetylcholine from triggering muscle contractions. This results in temporary paralysis, facilitating intubation and surgical manipulation. Atracurium is known for its rapid onset and intermediate duration of action, with metabolism independent of liver or kidney function, making it suitable for patients with organ impairments. Common side effects include hypotension and flushing. Its controlled muscle relaxation is crucial in modern anesthesia practices.