Atracurium oxalate

• CAT Number: R064935
• CAS Number: 64228-78-0
• Molecular Formula: C55H70N2O20
• Molecular Weight: 1079.159
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]propanoate;oxalic acid
• InChI: InChI=1S/C51H66N2O12.2C2H2O4/c1-56-42-14-12-34(28-44(42)58-3)26-40-38-32-48(62-7)46(60-5)30-36(38)16-20-52(40)22-18-50(54)64-24-10-9-11-25-65-51(55)19-23-53-21-17-37-31-47(61-6)49(63-8)33-39(37)41(53)27-35-13-15-43(57-2)45(29-35)59-4;2*3-1(4)2(5)6/h12-15,28-33,40-41H,9-11,16-27H2,1-8H3;2*(H,3,4)(H,5,6)
• InChIKey: NGJVDNJEQWIMBU-UHFFFAOYSA-N
• SMILES: COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2CCC(=O)OCCCCCOC(=O)CCN4CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)OC)OC)OC.C(=O)(C(=O)O)O.C(=O)(C(=O)O)O

Atracurium oxalate is a non-depolarizing neuromuscular blocking agent used in anesthesia to induce muscle relaxation during surgical procedures or mechanical ventilation. It works by competitively binding to nicotinic acetylcholine receptors at the neuromuscular junction, preventing acetylcholine from initiating muscle contraction. Atracurium is unique due to its breakdown via Hofmann elimination, a process independent of liver or kidney function, making it suitable for patients with organ impairments. It is commonly administered intravenously in controlled medical settings to provide short- to intermediate-term muscle paralysis, aiding in procedures requiring relaxed muscle tone, such as intubation or surgeries.