Auraptene

For research use only. Not for therapeutic Use.

  • CAT Number: R040647
  • CAS Number: 495-02-3
  • Molecular Formula: C19H22O3
  • Molecular Weight: 298.382
  • Purity: ≥95%
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Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-<wbr></wbr>7. It has anti-<wbr></wbr>inflammatory, anti-<wbr></wbr>carcinogenic, anti-<wbr></wbr>bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis. When examined for its potential use in Alzheimer’s disease treatment, auraptene was shown to inhibit β-<wbr></wbr>secretase (BACE1) activity with an IC<sub>50</sub> value of 345.1 μM.


CAS Number 495-02-3
Synonyms

7-[[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one; 7-(Geranyloxy)-coumarin; 7-[(3,7-Dimethyl-2,6-octadienyl)oxy]-coumarin; (E)-7-Geranoxycoumarin; 7-Geranyloxycoumarin; Aurapten; Aurapten (C19H22O3); Auraptene;

Molecular Formula C19H22O3
Purity ≥95%
Target MMP
Storage -20°C
IUPAC Name 7-[(2E)-3,7-dimethylocta-2,6-dienoxy]chromen-2-one
InChI InChI=1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+
InChIKey RSDDHGSKLOSQFK-RVDMUPIBSA-N
SMILES CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C

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