Aurora kinase inhibitor-8

• CAT Number: I027660
• CAS Number: 2133001-88-2
• Molecular Formula: C30H29N7O3
• Molecular Weight: 535.60
• Purity: ≥95%
• Synonyms: 4-(propanoylamino)-N-[4-[(5,8,11-trimethyl-6-oxopyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]phenyl]benzamide
• InChI: InChI=1S/C30H29N7O3/c1-5-26(38)32-20-9-7-19(8-10-20)28(39)33-21-11-13-22(14-12-21)34-30-31-17-25-27(35-30)36(3)24-15-6-18(2)16-23(24)29(40)37(25)4/h6-17H,5H2,1-4H3,(H,32,38)(H,33,39)(H,31,34,35)
• InChIKey: KGXBCWANASZZQG-UHFFFAOYSA-N
• SMILES: CCC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)NC3=NC=C4C(=N3)N(C5=C(C=C(C=C5)C)C(=O)N4C)C

Aurora kinase inhibitor-8 is a highly selective inhibitor of the Aurora kinases.

Reference

[1]. Ferguson FM, et al. Characterization of a highly selective inhibitor of the Aurora kinases. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4405-4408.
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