Autocamtide-2-related inhibitory peptide TFA

• CAT Number: I046270
• Molecular Formula: C66H126N22O21F3
• Molecular Weight: 1611.76
• Purity: ≥95%

Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
It is found that Autocamtide-2-related inhibitory peptide (TFA) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93, respectively, under the assay condition used[1].

Reference

[1]. Ishida A, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12.
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