Avizafone-d5 Dihydrobromide

• CAT Number: R047912
• CAS Number: 1356022-34-8
• Molecular Formula: C23H28ClN3O3
• Molecular Weight: 434.98
• Purity: ≥95%
• Synonyms: L-Lysyl-N-(2-benzoyl-4-chlorophenyl)-N-methyl-glycinamide-d5 Dihydrobromide; Prodiazepam-d5 Dihydrobromide; Ro 03-7355/000-d5 Dihydrobromide
• Storage: -20°C
• IUPAC Name: (2S)-2,6-diamino-N-[3-[4-chloro-2-(2,3,4,5,6-pentadeuteriobenzoyl)phenyl]-2-oxobutyl]hexanamide
• InChI: InChI=1S/C23H28ClN3O3/c1-15(21(28)14-27-23(30)20(26)9-5-6-12-25)18-11-10-17(24)13-19(18)22(29)16-7-3-2-4-8-16/h2-4,7-8,10-11,13,15,20H,5-6,9,12,14,25-26H2,1H3,(H,27,30)/t15?,20-/m0/s1/i2D,3D,4D,7D,8D
• InChIKey: WQRZTXVDPVPVDN-KAJGCMSNSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])C(=O)C2=C(C=CC(=C2)Cl)C(C)C(=O)CNC(=O)[C@H](CCCCN)N)[2H])[2H]

Avizafone-d5 Dihydrobromide（Cat No.:R047912） is a deuterated form of Avizafone, where five hydrogen atoms are replaced with deuterium, and it is presented as a dihydrobromide salt to enhance its solubility and stability. This compound is a prodrug of diazepam, used primarily for its anticonvulsant, anxiolytic, and sedative properties. The deuterated version is especially valuable for pharmacokinetic and metabolic studies, enabling precise analysis of Avizafone’s transformation into diazepam in the body. This helps in understanding the drug’s absorption, distribution, metabolism, and excretion, thereby aiding in the optimization of therapeutic strategies for treating anxiety and seizure disorders.