AZ-33

• CAT Number: I003400
• CAS Number: 1370290-34-8
• Molecular Formula: C25H27N3O6S
• Molecular Weight: 497.566
• Purity: ≥95%
• Synonyms: AZ-33; AZ 33; AZ33; LDHA Inhibitor 33.;2-(4-(4-((3-((2-Methylbenzo[d]thiazol-6-yl)amino)-3-oxopropyl)amino)-4-oxobutyl)benzyl)malonic acid
• Target: Lactate Dehydrogenase
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term or -20 °C for long term
• IUPAC Name: 2-[[4-[4-[[3-[(2-methyl-1,3-benzothiazol-6-yl)amino]-3-oxopropyl]amino]-4-oxobutyl]phenyl]methyl]propanedioic acid
• InChI: InChI=1S/C25H27N3O6S/c1-15-27-20-10-9-18(14-21(20)35-15)28-23(30)11-12-26-22(29)4-2-3-16-5-7-17(8-6-16)13-19(24(31)32)25(33)34/h5-10,14,19H,2-4,11-13H2,1H3,(H,26,29)(H,28,30)(H,31,32)(H,33,34)
• InChIKey: SGFJAJFBGVAOFW-UHFFFAOYSA-N
• SMILES: CC1=NC2=C(S1)C=C(C=C2)NC(=O)CCNC(=O)CCCC3=CC=C(C=C3)CC(C(=O)O)C(=O)O

AZ-33(CAT: I003400), also known as LDHA Inhibitor 33, is a small molecule compound that acts as an inhibitor of lactate dehydrogenase A (LDHA). LDHA is an enzyme involved in the process of anaerobic glycolysis, which is often upregulated in various types of cancer cells. By inhibiting LDHA, AZ-33 disrupts the metabolic activity of cancer cells and has the potential to impair their growth and survival. As an LDHA inhibitor, AZ-33 may have therapeutic applications in the treatment of cancer by targeting the altered metabolism of cancer cells.