For research use only. Not for therapeutic Use.
AZ PFKFB3 26 (Cat.No:I011269), also known as AZ67, is an inhibitor of the enzyme PFKFB3, which regulates glucose metabolism in cancer cells. This compound has shown promising anti-tumor activity in preclinical studies and is currently being investigated as a potential treatment for various types of cancer. Its CAS number is 1704740-52-2.
Catalog Number | I011269 |
CAS Number | 1704740-52-2 |
Synonyms | (2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide |
Molecular Formula | C24H26N4O2 |
Purity | ≥95% |
Target | Autophagy |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage | Store at -20℃ |
IUPAC Name | (2S)-N-[4-[3-cyano-1-(2-methylpropyl)indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide |
InChI | InChI=1S/C24H26N4O2/c1-16(2)14-28-15-17(13-25)21-12-20(9-10-23(21)28)30-19-7-5-18(6-8-19)27-24(29)22-4-3-11-26-22/h5-10,12,15-16,22,26H,3-4,11,14H2,1-2H3,(H,27,29)/t22-/m0/s1 |
InChIKey | OOGHGWKBJXQNEJ-QFIPXVFZSA-N |
SMILES | CC(C)CN1C=C(C2=C1C=CC(=C2)OC3=CC=C(C=C3)NC(=O)C4CCCN4)C#N |