AZ PFKFB3 26

• CAT Number: I011269
• CAS Number: 1704740-52-2
• Molecular Formula: C24H26N4O2
• Molecular Weight: 402.49
• Purity: ≥95%
• Synonyms: (2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide
• Target: Autophagy
• Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
• Storage: Store at -20℃
• IUPAC Name: (2S)-N-[4-[3-cyano-1-(2-methylpropyl)indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide
• InChI: InChI=1S/C24H26N4O2/c1-16(2)14-28-15-17(13-25)21-12-20(9-10-23(21)28)30-19-7-5-18(6-8-19)27-24(29)22-4-3-11-26-22/h5-10,12,15-16,22,26H,3-4,11,14H2,1-2H3,(H,27,29)/t22-/m0/s1
• InChIKey: OOGHGWKBJXQNEJ-QFIPXVFZSA-N
• SMILES: CC(C)CN1C=C(C2=C1C=CC(=C2)OC3=CC=C(C=C3)NC(=O)C4CCCN4)C#N

AZ PFKFB3 26 (Cat.No:I011269) is a small molecule inhibitor of PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3), an enzyme that regulates glycolysis by controlling the levels of fructose-2,6-bisphosphate. This compound is being studied for its potential to target cancer metabolism, as PFKFB3 is often upregulated in tumors to support the rapid energy demands of cancer cells. By inhibiting PFKFB3, AZ PFKFB3 26 aims to disrupt cancer cell metabolism, potentially offering a novel therapeutic strategy in oncology.