Azamethonium bromide

• CAT Number: I022829
• CAS Number: 306-53-6
• Molecular Formula: C13H33Br2N3
• Molecular Weight: 391.24
• Purity: 98%
• Synonyms: Azamethonium bromide; NSC 28858; NSC-28858; NSC28858
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: ethyl-[2-[2-[ethyl(dimethyl)azaniumyl]ethyl-methylamino]ethyl]-dimethylazanium;dibromide
• InChI: InChI=1S/C13H33N3.2BrH/c1-8-15(4,5)12-10-14(3)11-13-16(6,7)9-2;;/h8-13H2,1-7H3;2*1H/q+2;;/p-2
• InChIKey: UPCIBFUJJLCOQG-UHFFFAOYSA-L
• SMILES: CN(CC[N+](C)(CC)C)CC[N+](C)(CC)C.[Br-].[Br-]

Azamethonium Bromide(CAT: I022829) is a depolarizing neuromuscular blocking agent that functions by mimicking acetylcholine at nicotinic receptors on the neuromuscular junction. It causes sustained depolarization of the muscle membrane, leading to muscle paralysis. Azamethonium bromide is primarily used in neurological and muscular research to study neuromuscular transmission, receptor dynamics, and muscle relaxation mechanisms. Its ability to induce controlled muscle paralysis makes it a valuable tool for investigating synaptic function and the pharmacological modulation of neuromuscular disorders, aiding in the development of therapies for conditions like myasthenia gravis and other neuromuscular dysfunctions.