(+)-Azasetron hydrochloride

• CAT Number: M023983
• CAS Number: 123040-94-8
• Molecular Formula: C17H20ClN3O3.HCl
• Molecular Weight: 386.27
• Purity: ≥95%
• IUPAC Name: N-(1-azabicyclo[2.2.2]octan-3-yl)-6-chloro-4-methyl-3-oxo-1,4-benzoxazine-8-carboxamide;hydrochloride
• InChI: InChI=1S/C17H20ClN3O3.ClH/c1-20-14-7-11(18)6-12(16(14)24-9-15(20)22)17(23)19-13-8-21-4-2-10(13)3-5-21;/h6-7,10,13H,2-5,8-9H2,1H3,(H,19,23);1H
• SMILES: CN1C(=O)COC2=C(C=C(C=C21)Cl)C(=O)NC3CN4CCC3CC4.Cl

Selective 5-HT3 antagonist. (+)-enantiomer of Axon 1096 (racemic)
KEYWORDS: (+)-Azasetron hydrochloride | supplier | 5-HT3 antagonist | CAS [123040-94-8] | [123040-93-7] | [123040-69-7] | [123040-16-4] | Serotonin | 5-HT3 | Antagonist | Ion Channels | enantiomer | nausea | vomitting | cancer | chemotherapy

Reference

Y. Yamada et al. [Analysis of antiemetic effect of various dosage regimens of azasetron hydrochloride based on 5-HT3 receptor occupancy of serotonin]. Yakugaku Zasshi. 2007, 127, 353-357.