Azaspiracid-3

• CAT Number: R067738
• CAS Number: 265996-93-8
• Molecular Formula: C46H69NO12
• Molecular Weight: 828.053
• Purity: ≥95%
• Synonyms: (-)-Azaspiracid 3; 22-Demethylazaspiracid
• Storage: -20°C
• IUPAC Name: InChI=1S/C46H69NO12/c1-26-19-35-40-37(24-44(57-40)30(5)18-27(2)25-47-44)55-43(22-26,54-35)23-29(4)39-28(3)13-15-45(51,58-39)41(50)36-21-34-33(52-36)20-31(6)46(56-34)17-16-42(59-46)14-9-11-32(53-42)10-7-8-12-38(48)49/h7,9-10,14,26-28,30-37,39-41,47,50-51H,4,8,11-13,15-25H2,1-3,5-6H3,(H,48,49)/b10-7+/t26-,27+,28+,30-,31+,32-,33+,34+,35+,36-,37+,39+,40+,41+,42+,43+,44-,45-,46-/m1/s1
• InChI: InChI=1S/C46H69NO12/c1-26-19-35-40-37(24-44(57-40)30(5)18-27(2)25-47-44)55-43(22-26,54-35)23-29(4)39-28(3)13-15-45(51,58-39)41(50)36-21-34-33(52-36)20-31(6)46(56-34)17-16-42(59-46)14-9-11-32(53-42)10-7-8-12-38(48)49/h7,9-11,26-28,30-37,39-41,47,50-51H,4,8,12-25H2,1-3,5-6H3,(H,48,49)
• InChIKey: XGHMSEQYABFWLF-UHFFFAOYSA-N
• SMILES: CC1CCC(OC1C(=C)CC23CC(CC(O2)C4C(O3)CC5(O4)C(CC(CN5)C)C)C)(C(C6CC7C(O6)CC(C8(O7)CCC9(O8)CC=CC(O9)C=CCCC(=O)O)C)O)O

Azaspiracid-3 (CAS 265996-93-8) is a modulator of intracellular cAMP (cyclic adenosine monophosphate), calcium and pH levels.

Reference

1.Román, Yolanda, et al. "Effects of azaspiracids 2 and 3 on intracellular cAMP,[Ca2+], and pH." Chemical research in toxicology 17.10 (2004): 1338-1349.
2.Alfonso, Amparo, et al. "Azaspiracids modulate intracellular pH levels in human lymphocytes." Biochemical and biophysical research communications 346.3 (2006): 1091-1099.