AZD 3965-d3

• CAT Number: R014687
• CAS Number: NA
• Molecular Formula: C₂₁H₂₁D₃F₃N₅O₅S
• Molecular Weight: 518.52
• Purity: ≥95%
• Synonyms: 5-[[(4S)-4-Hydroxy-4-methyl-2-isoxazolidinyl]carbonyl]-3-methyl-d3-1-(1-methylethyl)-6-[[5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; (S)-5-(4-Hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-me
• Storage: Store at RT
• IUPAC Name: 5-[(4S)-4-hydroxy-4-methyl-1,2-oxazolidine-2-carbonyl]-6-[[5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]-1-propan-2-yl-3-(trideuteriomethyl)thieno[2,3-d]pyrimidine-2,4-dione
• InChI: InChI=1S/C21H24F3N5O5S/c1-9(2)29-18-14(16(30)27(5)19(29)32)13(17(31)28-7-20(4,33)8-34-28)12(35-18)6-11-10(3)25-26-15(11)21(22,23)24/h9,33H,6-8H2,1-5H3,(H,25,26)/t20-/m0/s1/i5D3
• InChIKey: PRNXOFBDXNTIFG-RPUPHZOYSA-N
• SMILES: CC1=C(C(=NN1)C(F)(F)F)CC2=C(C3=C(S2)N(C(=O)N(C3=O)C)C(C)C)C(=O)N4CC(CO4)(C)O

AZD3965-d3（Cat No.:R014687） is a deuterated version of AZD3965, where three hydrogen atoms are replaced with deuterium. This isotopic labeling enhances the stability of the molecule, making it particularly useful for pharmacokinetic and metabolic studies. AZD3965 is an experimental drug that targets the monocarboxylate transporter 1 (MCT1), which is involved in lactate transport across cell membranes. By inhibiting MCT1, AZD3965 aims to disrupt cancer cell metabolism, particularly in tumor environments that rely heavily on glycolysis for energy.