AZD1208

For research use only. Not for therapeutic Use.

  • CAT Number: I000752
  • CAS Number: 1204144-28-4
  • Molecular Formula: C₂₁H₂₁N₃O₂S
  • Molecular Weight: 379.48
  • Purity: ≥95%
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AZD1208(Cat No.:I000752) is a high-purity investigational compound essential for advanced pharmaceutical research and oncology studies. This potent and selective inhibitor of the Pim kinase family is crucial for investigating the pharmacokinetics, metabolism, and mechanisms of action in cancer therapies. AZD1208 plays a significant role in studying the inhibition of tumor growth and survival pathways. Widely used in research involving hematologic malignancies, solid tumors, and combination therapy strategies, AZD1208 integrates seamlessly into various experimental protocols, providing a robust and dependable solution for high-precision scientific investigations in drug development.


Catalog Number I000752
CAS Number 1204144-28-4
Synonyms

(5E)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-phenylphenyl]methylidene]-1,3-thiazolidine-2,4-dione

Molecular Formula C₂₁H₂₁N₃O₂S
Purity ≥95%
Target Pim
Solubility DMSO: ≥ 28.5 mg/mL
Storage Store at -20°C
IC50 < 5 nM
IUPAC Name (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-phenylphenyl]methylidene]-1,3-thiazolidine-2,4-dione
InChI InChI=1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/b18-12-/t16-/m1/s1
InChIKey MCUJKPPARUPFJM-UWCCDQBKSA-N
SMILES C1C[C@H](CN(C1)C2=C(C=CC=C2C3=CC=CC=C3)/C=C\4/C(=O)NC(=O)S4)N

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