AZD3264

• CAT Number: I002046
• CAS Number: 1609281-86-8
• Molecular Formula: C21H23N5O4S
• Molecular Weight: 441.50
• Purity: ≥95%
• Synonyms: 2-[(aminocarbonyl)amino]-5-[4-(3,5-dimethyl-4-isoxazolyl)-2-[(3S)-3-pyrrolidinyloxy]phenyl]-3-thiophenecarboxamide
• Target: IKK
• Solubility: DMSO: ≥ 48 mg/mL
• Storage: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• IUPAC Name: 2-(carbamoylamino)-5-[4-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(3S)-pyrrolidin-3-yl]oxyphenyl]thiophene-3-carboxamide
• InChI: InChI=1S/C21H23N5O4S/c1-10-18(11(2)30-26-10)12-3-4-14(16(7-12)29-13-5-6-24-9-13)17-8-15(19(22)27)20(31-17)25-21(23)28/h3-4,7-8,13,24H,5-6,9H2,1-2H3,(H2,22,27)(H3,23,25,28)/t13-/m0/s1
• InChIKey: NMFIXEFNQPDISY-ZDUSSCGKSA-N
• SMILES: CC1=C(C(=NO1)C)C2=CC(=C(C=C2)C3=CC(=C(S3)NC(=O)N)C(=O)N)OC4CCNC4

AZD3264（Cat No.:I002046） is a small molecule inhibitor specifically designed to target and inhibit the activity of IKK-epsilon and TBK1, two kinases involved in the regulation of inflammatory responses and immune signaling pathways. By blocking these kinases, AZD3264 aims to modulate the production of pro-inflammatory cytokines, offering potential therapeutic benefits for diseases characterized by excessive inflammation, such as autoimmune disorders and certain types of cancer. The inhibition of these pathways could lead to reduced inflammation and improved clinical outcomes in patients with inflammatory conditions, making AZD3264 a candidate for further clinical development in these areas.