For research use only. Not for therapeutic Use.
AZD8154（Cat No.:I022886） is a potent, high-purity compound designed for advanced pharmaceutical research, particularly in the study of respiratory and inflammatory diseases. As a selective dual inhibitor of PI3Kδ and PI3Kγ, AZD8154 is crucial for investigations into immune cell regulation and inflammatory response mechanisms. It facilitates precise studies in drug development, pharmacodynamics, and pharmacokinetics. With its well-defined chemical properties, AZD8154 ensures reliable and reproducible analytical results, enhancing the robustness of experimental data. Ideal for preclinical and clinical research, it integrates seamlessly into existing protocols, offering a dependable solution for high-precision scientific investigations.
| Catalog Number | I022886 |
| CAS Number | 2215022-45-8 |
| Synonyms | AZD8154; AZD 8154; AZD-8154; |
| Molecular Formula | C27H29N5O4S2 |
| Purity | 98% |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2-[(1S)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxopyrrolidin-1-yl)pyridin-2-yl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3H-isoindol-1-one |
| InChI | InChI=1S/C27H29N5O4S2/c1-15-25(37-27(28-15)30-21-6-4-7-22(29-21)31-11-5-8-23(31)33)18-12-19-14-32(16(2)17-9-10-17)26(34)24(19)20(13-18)38(3,35)36/h4,6-7,12-13,16-17H,5,8-11,14H2,1-3H3,(H,28,29,30)/t16-/m0/s1 |
| InChIKey | XOMFDZJQLSPGGV-INIZCTEOSA-N |
| SMILES | CC1=C(SC(=N1)NC2=NC(=CC=C2)N3CCCC3=O)C4=CC5=C(C(=C4)S(=O)(=O)C)C(=O)N(C5)C(C)C6CC6 |
