AZD9496 deacrylic acid phenol

• CAT Number: I040869
• CAS Number: 2173404-70-9
• Molecular Formula: C22H23F3N2O
• Molecular Weight: 388.43
• Purity: ≥95%
• Synonyms: 3,5-difluoro-4-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenol
• InChI: InChI=1S/C22H23F3N2O/c1-12-8-15-14-6-4-5-7-18(14)26-20(15)21(27(12)11-22(2,3)25)19-16(23)9-13(28)10-17(19)24/h4-7,9-10,12,21,26,28H,8,11H2,1-3H3/t12-,21-/m1/s1
• InChIKey: UQFNAXIUJPIITK-XUSGNXJCSA-N
• SMILES: CC1CC2=C(C(N1CC(C)(C)F)C3=C(C=C(C=C3F)O)F)NC4=CC=CC=C24

AZD9496 deacrylic acid phenol is a fragment of target protein ligand of PROTAC ER Degrader-4 (HY-135309)[1].

Reference

[1]. Bin Yang, et al. Compounds and their use in treating cancer. WO2019123367A1.