For research use only. Not for therapeutic Use.
AZD9496 is an investigational compound used in advanced pharmaceutical research, primarily focusing on breast cancer treatment. As a selective estrogen receptor degrader (SERD), AZD9496 binds to estrogen receptors and induces their degradation, effectively inhibiting estrogen-driven cancer cell growth. It is crucial for studying the pharmacokinetics, metabolism, and efficacy of SERDs in hormone receptor-positive breast cancer. AZD9496 offers potential as a therapeutic option for patients with endocrine-resistant breast cancer, making it a valuable tool in oncology research and drug development.
| Catalog Number | I002137 |
| CAS Number | 1639042-08-2 |
| Synonyms | (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid |
| Molecular Formula | C25H25F3N2O2 |
| Purity | ≥95% |
| Target | Estrogen Receptor/ERR |
| Solubility | DMSO: ≥ 104.5 mg/mL |
| Storage | Store at -20°C |
| IC50 | 0.7 nM(Ki); 0.14 nM(ER downregulation cell IC50) [1] |
| InChIKey | DFBDRVGWBHBJNR-BBNFHIFMSA-N |
