For research use only. Not for therapeutic Use.
Azide-PEG3-Tos (Cat No.:I016810) is a PROTAClinker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Azide-PEG3-Tos is also a non-cleavable ADClinker containing 3 units of PEG, which can be used to synthesize antibody-drug conjugates (ADCs).
| Catalog Number | I016810 |
| CAS Number | 178685-33-1 |
| Molecular Formula | C₁₃H₁₉N₃O₅S |
| Purity | ≥95% |
| Target | Antibody-drug Conjugate/ADC Related |
| IUPAC Name | 2-[2-(2-azidoethoxy)ethoxy]ethyl 4-methylbenzenesulfonate |
| InChI | InChI=1S/C13H19N3O5S/c1-12-2-4-13(5-3-12)22(17,18)21-11-10-20-9-8-19-7-6-15-16-14/h2-5H,6-11H2,1H3 |
| InChIKey | PTOJCKLTCKYNFG-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCN=[N+]=[N-] |
| Reference | [1]. Borchmann DE, et al. GRGDS-Functionalized Poly(lactide)-graft-poly(ethylene glycol) Copolymers: Combining Thiol-Ene Chemistry with Staudinger Ligation. Macromolecules. 2013 Jun 11;46(11):4426-4431.<br>[2]. Park, Tae Kyo, et al. Compound bearing beta-galactoside-introduced self-immolative linker. WO2018124758A2. |
