Azido Myristic Acid

• CAT Number: I042569
• CAS Number: 80667-36-3
• Molecular Formula: C12H23N3O2
• Molecular Weight: 241.33
• Purity: ≥95%
• Synonyms: 12-azidododecanoic acid
• InChI: InChI=1S/C12H23N3O2/c13-15-14-11-9-7-5-3-1-2-4-6-8-10-12(16)17/h1-11H2,(H,16,17)
• InChIKey: HYSGAVCDGKGYSZ-UHFFFAOYSA-N
• SMILES: C(CCCCCC(=O)O)CCCCCN=[N+]=[N-]

Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique[1].
Azido Myristic Acid could be a suitable substrate for enzymes. Due to the very small size of the azide group and its complete absence in any natural molecules the presence of azide group does affect the biodistribution of azido palmitic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.

Reference

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.
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