Azidoprazosin

For research use only. Not for therapeutic Use.

  • CAT Number: I022921
  • CAS Number: 90990-97-9
  • Molecular Formula: C21H21IN8O3
  • Molecular Weight: 560.36
  • Purity: 98%
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Azidoprazosin is a probe labeled with 125I.


Catalog Number I022921
CAS Number 90990-97-9
Synonyms

(125I)Iodoarylazidoprazosin; 125I-Iaap; Aryl azidoprazosin; Azidoprazosin; CP 65,526; Iodoaryl azidoprazosin

Molecular Formula C21H21IN8O3
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(4-azido-3-iodobenzoyl)-
InChI InChI=1S/C21H21IN8O3/c1-32-17-10-13-16(11-18(17)33-2)25-21(26-19(13)23)30-7-5-29(6-8-30)20(31)12-3-4-15(27-28-24)14(22)9-12/h3-4,9-11H,5-8H2,1-2H3,(H2,23,25,26)
InChIKey HCZCARLOZFORBR-UHFFFAOYSA-N
SMILES COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccc(N=N#N)c(I)c4
Reference

1. Greenberger LM. Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or immediately C-terminal to, transmembrane domains 6 and 12. J Biol Chem. 1993 May 25;268(15):11417-25. PMID: 8098711.
2. Greenberger LM, Yang CP, Gindin E, Horwitz SB. Photoaffinity probes for the alpha 1-adrenergic receptor and the calcium channel bind to a common domain in P-glycoprotein. J Biol Chem. 1990 Mar 15;265(8):4394-401. PMID: 1968459.

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