For research use only. Not for therapeutic Use.
Azilsartan trimethylethanolamine(Cat No.:I022925)is a combination drug consisting of azilsartan, an angiotensin II receptor blocker (ARB), and trimethylethanolamine, a stabilizing agent. Azilsartan works by blocking the action of angiotensin II, a hormone that narrows blood vessels and raises blood pressure, thereby lowering blood pressure in patients with hypertension. This medication is primarily used to treat high blood pressure (hypertension), helping to reduce the risk of stroke, heart failure, and kidney problems. The addition of trimethylethanolamine improves the solubility and stability of azilsartan, enhancing its effectiveness and bioavailability in the body.
Catalog Number | I022925 |
CAS Number | 1309776-70-2 |
Synonyms | Azilsartan trimethylethanolamine |
Molecular Formula | C30H33N5O6 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | 2-ethoxy-3-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate;2-hydroxyethyl(trimethyl)azanium |
InChI | InChI=1S/C25H20N4O5.C5H14NO/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22;1-6(2,3)4-5-7/h3-13H,2,14H2,1H3,(H,30,31)(H,27,28,32);7H,4-5H2,1-3H3/q;+1/p-1 |
InChIKey | RGPFEJSMFMFCIT-UHFFFAOYSA-M |
SMILES | CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)[O-].C[N+](C)(C)CCO |