For research use only. Not for therapeutic Use.
Azilsartan trimethylethanolamine is an angiotensin II receptor antagonist used in the treatment of hypertension.
Catalog Number | I022925 |
CAS Number | 1309776-70-2 |
Synonyms | Azilsartan trimethylethanolamine |
Molecular Formula | C30H33N5O6 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, 1-((2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)(1,1'-biphenyl)-4-yl)methyl)-2-ethoxy-1H-benzimidazole-7-carboxylate (1:1) |
InChI | InChI=1S/C25H20N4O5.C5H14NO/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22;1-6(2,3)4-5-7/h3-13H,2,14H2,1H3,(H,30,31)(H,27,28,32);7H,4-5H2,1-3H3/q;+1/p-1 |
InChIKey | RGPFEJSMFMFCIT-UHFFFAOYSA-M |
SMILES | CCOc1nc2cccc(C(=O)[O-])c2n1Cc3ccc(cc3)c4ccccc4C5=NOC(=O)N5.C[N+](C)(C)CCO |
Reference | 1: Naruse M, Koike Y, Kamei N, Sakamoto R, Yambe Y, Arimitsu M. Effects of azilsartan compared with telmisartan on insulin resistance in patients with essential hypertension and type 2 diabetes mellitus: An open-label, randomized clinical trial. PLoS One. 2019 Apr 3;14(4):e0214727. doi: 10.1371/journal.pone.0214727. eCollection 2019. PubMed PMID: 30943275; PubMed Central PMCID: PMC6447197. |