For research use only. Not for therapeutic Use.
Aztreonam ethyl ester（Cat No.:I022950） is a monobactam antibiotic that is primarily employed for the treatment of infections caused by gram-negative bacteria. It exhibits bactericidal activity by inhibiting the synthesis of bacterial cell walls. Aztreonam ethyl ester is effective against a wide range of gram-negative pathogens, including Pseudomonas aeruginosa. It is administered via intravenous or intramuscular routes and is commonly used in clinical settings to treat various infections, such as urinary tract infections, respiratory tract infections, intra-abdominal infections, and sepsis caused by susceptible bacteria.
| Catalog Number | I022950 |
| CAS Number | 102579-57-7 |
| Synonyms | Aztreonam ethyl ester |
| Molecular Formula | C15H21N5O8S2 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (2S,3S)-3-((Z)-2-(2-ammoniothiazol-4-yl)-2-(((1-ethoxy-2-methyl-1-oxopropan-2-yl)oxy)imino)acetamido)-2-methyl-4-oxoazetidine-1-sulfonate |
| InChI | InChI=1S/C15H21N5O8S2/c1-5-27-13(23)15(3,4)28-19-10(8-6-29-14(16)17-8)11(21)18-9-7(2)20(12(9)22)30(24,25)26/h6-7,9H,5H2,1-4H3,(H2,16,17)(H,18,21)(H,24,25,26)/b19-10-/t7-,9-/m0/s1 |
| InChIKey | GHYPJWICYOYVRU-AICXJHAVSA-N |
| SMILES | CCOC(=O)C(C)(C)ON=C(/C(=O)N[C@H]1[C@H](C)N(C1=O)S(=O)(=O)[O-])c2csc([NH3+])n2 |
| Reference | 1: Gaeta F, Valluzzi RL, Alonzi C, Maggioletti M, Caruso C, Romano A. Tolerability of aztreonam and carbapenems in patients with IgE-mediated hypersensitivity to penicillins. J Allergy Clin Immunol. 2015 Apr;135(4):972-6. doi: 10.1016/j.jaci.2014.10.011. Epub 2014 Nov 22. PubMed PMID: 25457154. |
