For research use only. Not for therapeutic Use.
Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite (Item No. <span class=/itemid/>81565</span>), hypochlorous acid, and hydrogen peroxide. It reacts directly and rapidly with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA stoichiometrically at a 1:1 ratio into a fluorescent product that can be examined at an excitation of 332 nm and emission > 400 nm.
| Catalog Number | R016693 |
| CAS Number | 1357078-03-5 |
| Synonyms | Coumarin Boronic Acid |
| Molecular Formula | C9H7BO4 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | (2-oxochromen-7-yl)boronic acid |
| InChI | InChI=1S/C9H7BO4/c11-9-4-2-6-1-3-7(10(12)13)5-8(6)14-9/h1-5,12-13H |
| InChIKey | MUZVCJQIBNTECF-UHFFFAOYSA-N |
| SMILES | B(C1=CC2=C(C=C1)C=CC(=O)O2)(O)O |
