For research use only. Not for therapeutic Use.
B-HT 920 (Talipexole dihydrochloride)(CAT: I003323) is a multifunctional compound acting as a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist. It is widely studied for its anti-Parkinsonian activity, offering insights into the modulation of motor symptoms and neuroprotection in Parkinson’s disease models. B-HT 920 is also valuable for investigating the role of these receptors in neurological and psychiatric conditions. With high specificity and efficacy, this compound serves as a critical tool in neuroscience research, advancing the development of therapeutic strategies for Parkinson’s disease and related disorders.
| Catalog Number | I003323 |
| CAS Number | 36085-73-1 |
| Synonyms | 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d]azepin-2-amine, dihydrochloride |
| Molecular Formula | C10H15N3S • 2HCl |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | 100 mM in water; 100 mM in DMSO ; |
| Storage | -20°C |
| IC50 | 25 nM(Adrenergic receptor α-2, rat) |
| IUPAC Name | 6-prop-2-enyl-4,5,7,8-tetrahydro-[1,3]thiazolo[4,5-d]azepin-2-amine;dihydrochloride |
| InChI | InChI=1S/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8;;/h2H,1,3-7H2,(H2,11,12);2*1H |
| InChIKey | DPQAXNSOFFYKDS-UHFFFAOYSA-N |
| SMILES | C=CCN1CCC2=C(CC1)SC(=N2)N.Cl.Cl |
