For research use only. Not for therapeutic Use.
B-Raf IN 15(CAT: I040926) is a selective inhibitor targeting B-Raf, a key kinase in the Ras-Raf-MEK-ERK signaling pathway, which plays a critical role in regulating cell growth and differentiation. Mutations in B-Raf, particularly the V600E mutation, are commonly associated with various cancers, including melanoma, colorectal, and thyroid cancers. By inhibiting B-Raf, B-Raf IN 15 disrupts downstream signaling, leading to decreased tumor cell proliferation and survival. This compound is highly relevant for Cancer Disease Research, particularly in developing targeted therapies for cancers with B-Raf mutations, offering a promising approach for personalized cancer treatment.
| CAS Number | 832107-31-0 |
| Synonyms | 7-[(pyridin-3-ylamino)-thiophen-3-ylmethyl]quinolin-8-ol |
| Molecular Formula | C19H15N3OS |
| Purity | ≥95% |
| IUPAC Name | 7-[(pyridin-3-ylamino)-thiophen-3-ylmethyl]quinolin-8-ol |
| InChI | InChI=1S/C19H15N3OS/c23-19-16(6-5-13-3-1-9-21-18(13)19)17(14-7-10-24-12-14)22-15-4-2-8-20-11-15/h1-12,17,22-23H |
| InChIKey | KSWFNFIKRRTNCX-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C(=C(C=C2)C(C3=CSC=C3)NC4=CN=CC=C4)O)N=C1 |
