B102(PARP/HDAC-IN-1)

• CAT Number: I047177
• Purity: ≥95%

B102(PARP/HDAC-IN-1) is a dual inhibitor of PARP and HDAC, with IC50 of 19.01 nM, 2.13 nM, 1.69 μM, > 10 μM for PARP1, PARP2, HDAC1, HDAC6, respectively, in an enzymatic assay. It exhibits anti-proliferative and anti-tumor effects. It also induces DNA damage and apoptosis in vitro.

Reference

[1] Zhu Q, et al. Cell Death Dis. 2024 Jan 5;15(1):10.