BAD (103-127) (human)

• CAT Number: I044292
• CAS Number: 331762-68-6
• Molecular Formula: C137H212N42O39S
• Molecular Weight: 3103.47
• Purity: ≥95%

BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL. BAD (103-127) (human) is reported to have almost 800-fold higher affinity for Bcl-XL than the 16-mer peptide[1].

Reference

[1]. Dilraj Lama, et al. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L). J Comput Aided Mol Des. 2011 May;25(5):413-26.
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