Bakkenolide A

• CAT Number: R072428
• CAS Number: 19906-72-0
• Molecular Formula: C15H22O2
• Molecular Weight: 234.33
• Purity: ≥95%
• Synonyms: (2R,3aR,7S,7aR)-7,7a-dimethyl-4′-methylidenespiro[3,3a,4,5,6,7-hexahydro-1H-indene-2,3′-oxolane]-2′-one
• InChI: InChI=1S/C15H22O2/c1-10-5-4-6-12-7-15(9-14(10,12)3)11(2)8-17-13(15)16/h10,12H,2,4-9H2,1,3H3/t10-,12+,14+,15+/m0/s1
• InChIKey: OVXAYHNZXBOVPV-QMGNLALYSA-N
• SMILES: CC1CCCC2C1(CC3(C2)C(=C)COC3=O)C

Bakkenolide A is a natural product extracted from Petasites tricholobus. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways[1].

Reference

[1]. Zhang L, et al. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways. Biomed Pharmacother. 2016 Oct;83:958-966.
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