For research use only. Not for therapeutic Use.
BAM15(CAT: I002807) is a mitochondrial uncoupler widely studied for its role in modulating mitochondrial membrane potential and energy metabolism. Unlike classical uncouplers, BAM15 does not stimulate proton leak-dependent reactive oxygen species (ROS) production, making it a valuable tool for investigating metabolic diseases, obesity, and aging. It facilitates mitochondrial respiration by dissipating the proton gradient, promoting energy expenditure without compromising ATP synthesis. BAM15 is also utilized in exploring therapeutic strategies for conditions such as type 2 diabetes and neurodegenerative diseases. Its specificity and efficacy make it a reliable compound for advancing mitochondrial biology and metabolic research.
| Catalog Number | I002807 |
| CAS Number | 210302-17-3 |
| Synonyms | BAM15; BAM-15; BAM 15.;N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine |
| Molecular Formula | C16H10F2N6O |
| Purity | ≥95% |
| Target | Oxidative Phosphorylation |
| Solubility | Soluble in DMSO, not in water |
| Storage | -20°C |
| IUPAC Name | 5-N,6-N-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine |
| InChI | InChI=1S/C16H10F2N6O/c17-9-5-1-3-7-11(9)19-13-14(20-12-8-4-2-6-10(12)18)22-16-15(21-13)23-25-24-16/h1-8H,(H,19,21,23)(H,20,22,24) |
| InChIKey | OEGJBRZAJRPPHL-UHFFFAOYSA-N |
| SMILES | FC1=CC=CC=C1NC2=NC3=NON=C3N=C2NC4=C(F)C=CC=C4 |
