Baohuoside I

  • CAT Number: I000512
  • CAS Number: 113558-15-9
  • Molecular Formula: C27H30O10
  • Molecular Weight: 514.52
  • Purity: ≥95%
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Baohuoside I (Cat No.:I000512) is a natural flavonol glycoside compound extracted from Epimedium sagittatum. It exhibits pharmacological actions such as osteoprotective effects, promoting bone formation, and inhibiting bone resorption, making it potentially useful in the treatment of osteoporosis and related conditions. Additionally, baohuoside I has been studied for its aphrodisiac properties, suggesting potential applications in enhancing sexual function and libido. Further research is ongoing to elucidate its specific targets and mechanisms of action, as well as explore its potential therapeutic uses in drug development and other relevant areas.


Catalog Number I000512
CAS Number 113558-15-9
Synonyms

Icariside-II

Molecular Formula C27H30O10
Purity ≥95%
Target CXCR4
Solubility DMSO:32 mg/mL
Storage Store at -20°C
IUPAC Name 5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
InChI InChI=1S/C27H30O10/c1-12(2)5-10-16-17(28)11-18(29)19-21(31)26(37-27-23(33)22(32)20(30)13(3)35-27)24(36-25(16)19)14-6-8-15(34-4)9-7-14/h5-9,11,13,20,22-23,27-30,32-33H,10H2,1-4H3/t13-,20-,22+,23+,27-/m0/s1
InChIKey NGMYNFJANBHLKA-LVKFHIPRSA-N
SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C(=CC(=C3C2=O)O)O)CC=C(C)C)C4=CC=C(C=C4)OC)O)O)O
Reference

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[1]. Kim B, et al. Baohuoside I Suppresses Invasion of Cervical and Breast Cancer Cells through the Downregulation of CXCR4 Chemokine Receptor Expression. Biochemistry. 2014 Dec 9;53(48):7562-9.&nbsp;
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[2]. Wu J, et al. Icariside II induces apoptosis via inhibition of the EGFR pathways in A431 human epidermoid carcinoma cells. Mol Med Rep. 2013 Aug;8(2):597-602.&nbsp;
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[3]. Wu J, et al. Icariside II induces apoptosis of melanoma cells through the downregulation of survival pathways. Nutr Cancer. 2013;65(1):110-7.&nbsp;
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[4]. Huang C, et al. Induction of apoptosis by Icariside II through extrinsic and intrinsic signaling pathways in human breast cancer MCF7 cells. Biosci Biotechnol Biochem. 2012;76(7):1322-8.
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