BAPTA-AM

• CAT Number: R020566
• CAS Number: 126150-97-8
• Molecular Formula: C34H40N2O18
• Molecular Weight: 764.7
• Purity: ≥95%
• Synonyms: N,N’-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1’-Bis[(acetyloxy)methyl] Ester; BAPTA-AM;?1,2-Bis(2-aminophenoxy)ethane-N,N,N’,N’-tetraacetic Acid Tetraacetoxymethyl Ester
• Target: Potassium Channel
• Storage: -20°C
• IUPAC Name: acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]phenoxy]ethoxy]anilino]acetate
• InChI: InChI=1S/C34H40N2O18/c1-23(37)47-19-51-31(41)15-35(16-32(42)52-20-48-24(2)38)27-9-5-7-11-29(27)45-13-14-46-30-12-8-6-10-28(30)36(17-33(43)53-21-49-25(3)39)18-34(44)54-22-50-26(4)40/h5-12H,13-22H2,1-4H3
• InChIKey: YJIYWYAMZFVECX-UHFFFAOYSA-N
• SMILES: CC(=O)OCOC(=O)CN(CC(=O)OCOC(=O)C)C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

BAPTA-AM(CAT: R020566) is a membrane-permeable calcium chelator widely used in biochemical and physiological research. Upon entering cells, BAPTA-AM is cleaved by intracellular esterases, releasing BAPTA, which effectively buffers intracellular calcium ions. This property makes BAPTA-AM invaluable for studying calcium signaling pathways, neuronal activity, and various cellular processes that are calcium-dependent. Its application spans research in neurobiology, muscle physiology, and signal transduction. BAPTA-AM’s ability to precisely control intracellular calcium levels without altering external calcium concentrations allows researchers to dissect calcium-dependent mechanisms with high specificity.