BAPTA

• CAT Number: I005115
• CAS Number: 85233-19-8
• Molecular Formula: C22H24N2O10
• Molecular Weight: 476.41
• Purity: ≥95%
• Synonyms: 2,2/’,2/’/’,2/’/’/’-(((ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(azanetriyl))tetraacetic acid
• Target: Phospholipase
• Solubility: DMSO: ≥ 26 mg/mL
• Storage: Store at +4℃
• IUPAC Name: 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid
• InChI: InChI=1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
• InChIKey: FTEDXVNDVHYDQW-UHFFFAOYSA-N
• SMILES: C1=CC=C(C(=C1)N(CC(=O)O)CC(=O)O)OCCOC2=CC=CC=C2N(CC(=O)O)CC(=O)O

BAPTA(CAT: I005115) is a highly selective calcium chelator widely used in neuropharmacology and related biomedical research. As a calcium ion (Ca²⁺) buffer, BAPTA binds free calcium with high affinity, effectively controlling intracellular calcium concentrations without interfering with magnesium ions or pH levels. This mechanism makes it invaluable for studies on calcium signaling pathways, synaptic transmission, and neuronal excitability. BAPTA’s precise chelation properties enable the investigation of calcium-dependent processes in neurodegenerative disorders, synaptic plasticity, and excitotoxicity. Its application extends to understanding calcium’s role in cell death and survival pathways, supporting advanced research in neurological diseases and therapeutic development.